“Pharmaceutical Digital Design: From Chemical Structure through Crystal Polymorph to Conceptual Crystallization Process”
Solid-State Chemistry
Experience • Partnership • solutions
Solid Form Design
SuRE Pharma Consulting provides deep technical expertise in solid-state chemistry needed to search for and evaluate solid forms of preclinical candidates, all to ensure the right form is selected the first time.
Crystallization
SuRE Pharma Consulting brings 30+ years experience in crystallizing small molecules, be it for the first time or in an optimal solid form, to meet design specifications, ensure process control and minimize risk.
Patent/Expert Witnessing
SuRE Pharma Consulting counsels legal teams on constructing and defending claims to crystal forms that are based on sound science and best practices, key to maximizing their intellectual property value.
Introducing SuRE Pharma Consulting, LLC
Over three decades, first as a solid-state scientist at Eli Lilly and Company and more recently as Head of Science at the Cambridge Crystallographic Data Centre, I have had the privilege of working with amazing scientists to navigate the challenges of developing small molecule drugs and to help advance tools to study pharmaceutical solids. Along the way, BIG lessons have come from working with many small molecules. I learned, for example, that you can only design for and around solid forms that you know about, and that when it comes to their solid-state chemistry, all molecules are different, no matter how similar they appear to be. Although I have learned (and also likely forgotten) a fair amount about how to manage complexity when dealing with small molecule crystal forms, perhaps the biggest lesson has been to never be afraid to “phone a friend” for help.
In 2023, I decided to embark on a new journey, one where I could be that “friend on speed dial” to organizations interested in tapping into my expertise in solid form development. SuRE Pharma Consulting, LLC aims to leverage my experience in solid form development in partnership with companies, big and small, to provide solutions needed to ensure the smooth transformation of molecules into medicines.
Susan M. Reutzel-Edens, President
Our Services
scientific consulting
SuRE Pharma Consulting partners with your team to ensure that the solid form of your drug meets your drug product performance criteria and that your data package is submission ready.
legal consulting
SuRE Pharma Consulting works with your team of scientists and patent attorneys to formulate a robust patent strategy that will secure IP rights to your discoveries and help protect your investments.
training
SuRE Pharma Consulting offers bespoke training, delivered via webinar or in-house, on a range of topics related to the solid-state chemistry of drugs.
News & Notes
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Now out in Crystal Growth & Design!
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Now published in Nature!
“Predicting crystal form stability under real-world conditions”, an Avant-garde Materials Simulation led effort to redefine the state-of-the-art in predicting free energies of crystals!
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Now published in Chemical Science!
“Do metastable polymorphs always grow faster?” Fantastic collaboration with Pietro Sacchi and Aurora Cruz-Cabeza!